tDHU, acid

Tocris Bioscience | Catalog # 7773

Functionalized cereblon ligand for PROTAC development
Tocris Bioscience

Key Product Details

Description

Functionalized cereblon ligand for PROTAC development
View all Degrader Building Blocks »

Product Description

tDHU, acid is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a benzoic acid functional handle for ready conjugation to a linker/target protein ligand.

Part of a range of functionalized tool molecules for PROTAC® Degrader R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Product Specifications for tDHU, acid

Molecular Weight

248.24

Formula

C12H12N2O4

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

4-Methyl-3-(tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)benzoic acid

CAS Number

2377643-37-1

PubChem ID

139534352

InChI Key

NXRZIUASGSMTJJ-UHFFFAOYSA-N

SMILES

O=C(C1=CC=C(C)C(N2C(NC(CC2)=O)=O)=C1)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for tDHU, acid

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for tDHU, acid

For research use only

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