Chemical Name: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-piperazine hydrochloride
Biological ActivityTerazosin hydrochloride is a α1- and α2B-adrenoceptor antagonist (Ki values are 3.3, 0.7, 1.1, 7.7, 1510 and 78.2 nM for α1A, α1B, α1D, α2B, α2A and α2C receptors respectively). Antihypertensive following oral or intravenous administration in vivo.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Pharmacology of tera.
Actions of tera. and its enantiomers at subtypes of α1- and α2-adrenoceptors in vitro.
Hancock et al.
J.Recept.Signal Transduct.Res., 1995;15:863
Comparison of displacemental potencies of tera. enantiomers for α1-adrenoceptor subtypes.
Maruyama et al.
Citations for Terazosin hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Terazosin hydrochloride include:
2 Citations: Showing 1 - 2
The anti-hypertensive drug pra. inhibits glioblastoma growth via the PKCδ-dependent inhibition of the AKT pathway.
Authors: Kahn Et al.
EMBO Mol Med 2016;8:511
Medullary NE neurons modulate local oxygen concentrations in the bed nucleus of the stria terminalis.
Authors: Bucher Et al.
J Cereb Blood Flow Metab 2014;34:1128
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