Terazosin hydrochloride

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Terazosin hydrochloride | CAS No. 63074-08-8 | Adrenergic alpha-1 Receptor Antagonists
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Description: α1 and α2B antagonist (α1 > α2B). Orally active

Chemical Name: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-piperazine hydrochloride

Purity: ≥99%

Product Details
Citations (2)
Supplemental Products

Biological Activity

Terazosin hydrochloride is a α1- and α2B-adrenoceptor antagonist (Ki values are 3.3, 0.7, 1.1, 7.7, 1510 and 78.2 nM for α1A, α1B, α1D, α2B, α2A and α2C receptors respectively). Antihypertensive following oral or intravenous administration in vivo.

Technical Data

Soluble to 50 mM in water with gentle warming
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Pharmacology of tera.
    Am.J.Med., 1986;80:12
  2. Actions of tera. and its enantiomers at subtypes of α1- and α2-adrenoceptors in vitro.
    Hancock et al.
    J.Recept.Signal Transduct.Res., 1995;15:863
  3. Comparison of displacemental potencies of tera. enantiomers for α1-adrenoceptor subtypes.
    Maruyama et al.
    Biol.Pharm.Bull., 1994;17:1126

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Citations for Terazosin hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Terazosin hydrochloride include:

2 Citations: Showing 1 - 2


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