Catalog Number: 1506
Chemical Name: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-piperazine hydrochloride
Biological Activity
α1- and α2B-adrenoceptor antagonist (Ki values are 3.3, 0.7, 1.1, 7.7, 1510 and 78.2 nM for α1A, α1B, α1D, α2B, α2A and α2C receptors respectively). Antihypertensive following oral or intravenous administration in vivo.
Technical Data
  • M.Wt:
    423.9
  • Formula:
    C19H25N5O4.HCl
  • Solubility:
    Soluble to 50 mM in water with gentle warming
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    63074-08-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Pharmacology of terazosin.
    Kyncl
    Am.J.Med., 1986;80:12
  2. Actions of terazosin and its enantiomers at subtypes of α1- and α2-adrenoceptors in vitro.
    Hancock et al.
    J.Recept.Signal Transduct.Res., 1995;15:863
  3. Comparison of displacemental potencies of terazosin enantiomers for α1-adrenoceptor subtypes.
    Maruyama et al.
    Biol.Pharm.Bull., 1994;17:1126
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Terazosin hydrochloride include:

1 Citations: Showing 1 - 1

  1. Medullary norepinephrine neurons modulate local oxygen concentrations in the bed nucleus of the stria terminalis.
    Authors: Bucher Et al.
    J Cereb Blood Flow Metab 2014;34:1128

Have you used Terazosin hydrochloride?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

Feedback

Customer Information