Teriflunomide

   
Product Datasheet
Catalog Number:5069
Alternate Names:A77 1726
Chemical Name:2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide
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Biological Activity
Inhibitor of dihydroorotate dehydrogenase (Kd = 12 nM; Ki = 179 nM). Inhibits proliferation of mitogen- or cytokine-stimulated lymphoid cells in vitro by inhibiting cell cycle progression from G1 to S. Imunosuppressive agent. Active metabolite of leflunomide (Cat. No. 2228).
Technical Data
  • M.Wt:
    270.21
  • Formula:
    C12H9F3N2O2
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    108605-62-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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