Teriflunomide

Catalog # Availability Size / Price Qty
5069/50
Dehydrogenase Inhibitors Small Molecule
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Description: Inhibitor of DHODH; active metabolite of Leflunomide
Alternative Names: A77 1726

Chemical Name: 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide

Purity: ≥99%

Product Details
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Biological Activity

Inhibitor of dihydroorotate dehydrogenase (Kd = 12 nM; Ki = 179 nM). Inhibits proliferation of mitogen- or cytokine-stimulated lymphoid cells in vitro by inhibiting cell cycle progression from G1 to S. Imunosuppressive agent. Active metabolite of leflunomide (Cat. No. 2228).

Technical Data

M.Wt:
270.21
Formula:
C12H9F3N2O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
108605-62-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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