Catalog Number: 4339
Biological Activity
Blocker of Kir1.1 channels; displays >250-fold selectivity for Kir1.1 (Kd values are 1.1, 274 and 361 nM for Kir1.1, Kir3.1/3.2 and Kir3.1/3.4 respectively). Derivative of tertiapin-Q (Cat. No. 1316).
Technical Data
  • M.Wt:
    2428.03
  • Formula:
    C106H179N33O24S4
  • Sequence:
    ALCNCNRIIIPLQCWKKCGKK

    (Modifications: Disulfide bridge between 3 - 14, 5 - 18, Lys-21 = C-terminal amide)

  • Solubility:
    Soluble to 2 mg/ml in 20% acetonitrile / water
  • Storage:
    Store at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Engineered specific and high-affinity inhibitor for a subtype of inward-rectifier K+ channels.
    Ramu et al.
    Proc.Natl.Acad.Sci.USA, 2008;105:10774
Tocris Peptides
Description Application Cat# Citations Images  

Tertiapin-Q

1316 5  
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