Thalidomide 4'-oxyacetamide-alkylC6-amine

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Thalidomide 4'-oxyacetamide-alkylC6-amine | CAS No. 2376990-31-5 | Degrader Building Blocks
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Description: Cereblon ligand with alkyl linker and terminal amine for onward chemistry
Alternative Names: Thalidomide - linker 15

Chemical Name: N-(6-Aminohexyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide hydrochloride

Product Details
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Biological Activity

Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkyl linker with amine terminal ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

This product has been recently renamed. The previous name for this product was Thalidomide - linker 15

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Technical Data

Formula:
C21H26N4O6.HCl
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in DMF
Storage:
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
CAS No:
2376990-31-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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