Thrombin Receptor Agonist Peptide

Name: Thrombin Receptor Agonist Peptide
Brand: Tocris Bioscience
SKU: 1185
Price: 264 USD
Availability: InStock

Tocris Bioscience | Catalog # 1185

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Citations (6)

Product Documents

Causes platelet aggregation and secretion

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Causes platelet aggregation and secretion

Alternative Names

TRAP

View all Protease-Activated Receptor Agonists »

Product Description

Thrombin Receptor Agonist Peptide is an agonist at the thrombin receptor; causes platelet aggregation (EC₅₀ = 4 μM) and secretion.

Product Specifications for Thrombin Receptor Agonist Peptide

Molecular Weight

1739.95

Formula

C₈₁H₁₁₈N₂₀O₂₃

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

137339-65-2

PubChem ID

16131180

InChI Key

OXHYRVSBKWIFES-WWSDOYNLSA-N

SMILES

[H]N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 0.9mg/ml in water

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

Vassallo Structure-function relationships in the activation of platelet thrombin receptors by receptor-derived peptides. J.Biol.Chem. 1992 PMID: 1313429
Vu Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 1991 PMID: 1672265
Huang 'Thrombin' receptor-directed ligand accounts for activation by thrombin of platelet phospholipase C and accumulation of 3-phosphorylated phosphoinositides. J.Biol.Chem. 1991 PMID: 1655750

Product Documents for Thrombin Receptor Agonist Peptide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Thrombin Receptor Agonist Peptide

For research use only

Citations for Thrombin Receptor Agonist Peptide

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