Selective facilitator of 5-HT uptake in vitro
and in vivo
. Has no affinity for a wide range of receptors, including 5-HT and dopamine (IC50
> 10 μ
M) and has no effect on noradrenalin or dopamine uptake. Antidepressant, analgesic and neuroprotective following systemic administration in vivo
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Neurochemical profile of tianeptine, a new antidepressant drug.
Kato and Weitsch
Analgesic effect of tianeptine in mice.
Uzbay et al.
Life Sci., 1999;64:1313
Neuroprotective properties of tianeptine: interactions with cytokines.
Plaisant et al.
Tianeptine, a selective enhancer of serotonin uptake in rat brain.
Mennini et al.
The citations listed below are publications that use Tocris products. Selected citations for Tianeptine sodium salt include:
Showing Results 1 - 2 of 2