Recombinant Human TIFA His Protein

Novus Biologicals | Catalog # NBP1-99103

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

Immunoprecipitation, SDS-PAGE
View all TIFA Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-184 of Human TIFA

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMTSFED ADTEETVTCL QMTVYHPGQL QCGIFQSISF NREKLPSSEV VKFGRNSNIC HYTFQDKQVS RVQFSLQLFK KFNSSVLSFE IKNMSKKTNL IVDSRELGYL NKMDLPYRCM VRFGEYQFLM EKEDGESLEF FETQFILSPR SLLQENNWPP HRPIPEYGTY SLCSSQSSSP TEMDENES

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

24 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Application Notes

Use in IP reported in scientific literature (PMID:35089437).

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human TIFA His Protein

Recombinant Human TIFA Protein [NBP1-99103]

Formulation, Preparation, and Storage

NBP1-99103
Formulation 20 mM Tris-HCl buffer (pH8.0), 20% glycerol, 1 mM DTT
Preservative No Preservative
Concentration 0.5 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TIFA

TIFA, also known as TRAF-interacting protein with FHA domain-containing protein A, is an adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. This protein induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism. Recombinant human TIFA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Alternate Names

Putative MAPK-activating protein PM14, Putative NF-kappa-B-activating protein 20, T2BPMGC20791, T6BP, TIFAA, TRAF2 binding protein, TRAF2-binding protein, TRAF6 binding protein, TRAF-interacting protein with a forkhead-associated domain, TRAF-interacting protein with FHA domain-containing protein A, TRAF-interacting protein with forkhead-associated domain

Gene Symbol

TIFA

Additional TIFA Products

Product Documents for Recombinant Human TIFA His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human TIFA His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Citations for Recombinant Human TIFA His Protein

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