Catalog Number: 3051
Biological Activity
VGF-derived peptide; spans residues 556-576 of the precursor sequence. Protects cerebellar granule cells (CGCs) from serum and potassium deprivation-induced apoptosis. Increases energy expenditure and prevents early phase diet-induced diabetes.
Technical Data
  • M.Wt:
    2432.77
  • Formula:
    C107H170N40O26
  • Sequence:
    TLQPPASSRRRHFHHALPPAR
  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    869988-94-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. TLQP-21, a neuroendocrine VGF-derived peptide, prevents cerebellar granule cell death induced by serum and potassium deprivation.
    Severini et al.
    J.Neurochem., 2008;104:534
  2. TLQP-21, a VGF-derived peptide, increases energy expenditure and prevents the early phase of diet-induced obesity.
    Bartolomucci et al.
    Proc.Natl.Acad.Sci. USA, 2006;103:14584
Citations:

The citations listed below are publications that use Tocris products. Selected citations for TLQP 21 include:

1 Citations: Showing 1 - 1

  1. Identification of the C3a receptor (C3AR1) as the target of the VGF-derived peptide TLQP-21 in rodent cells.
    Authors: Hannedouche Et al.
    Front Pharmacol 2013;288:27434

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