Catalog # Availability Size / Price Qty
Chemiluminescent Substrates Small Molecule
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Description: NIR-emission luciferin analog; orally bioavailable and brain penetrant
Alternative Names: AkaLumine HCl

Chemical Name: (4S)-2-[(1E,3E)-4-[4-(Dimethylamino)phenyl]-1,3-butadien-1-yl]-4,5-dihydro-4-thiazolecarboxylic acid hydrochloride

Purity: ≥90%

Product Details

Biological Activity

Near-infrared red (NIR)-emission luciferin analog. Peak luminescence at 677 nM. ~40-fold brighter than luciferase. 100-1000 times brighter in vivo than conventional systems. Allows non-invasive visualization of single cells deep inside freely moving animals. Orally bioavailable and brain penetrant.

The batch molecular weight of the product may vary significantly due to hydration level. Please refer to the Certificate of Analysis for the current batch.

Technical Data

Soluble to 5 mg/ml in water with gentle warming and to 10 mg/ml in DMSO
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:
This compound contains a relatively high proportion of water of hydration. This is introduced during the manufacturing process. Please check the Certificate of Analysis for batch specific details.

Product Datasheets

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).


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