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Chemiluminescent Substrates Small Molecule
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Description: NIR-emission luciferin analog; orally bioavailable and brain penetrant
Alternative Names: AkaLumine HCl

Chemical Name: (4S)-2-[(1E,3E)-4-[4-(Dimethylamino)phenyl]-1,3-butadien-1-yl]-4,5-dihydro-4-thiazolecarboxylic acid hydrochloride

Purity: ≥90%

Product Details

Biological Activity

Near-infrared red (NIR)-emission luciferin analog. Peak luminescence at 677 nM. ~40-fold brighter than luciferase. 100-1000 times brighter in vivo than conventional systems. Allows non-invasive visualization of single cells deep inside freely moving animals. Orally bioavailable and brain penetrant.

This product is supplied as a hydrochloride salt, the stoichiometry of which is batch dependant. Please refer to the Certificate of Analysis to obtain the batch specific Net Product Content.

Technical Data

Soluble to 5 mg/ml in water with gentle warming and to 10 mg/ml in DMSO
Store at -20°C
M. Wt
302.39 (Free Base)

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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