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TokeOni | Bioluminescent Substrates
1 Image
Description: NIR-emission luciferin analog; ideal for deep tissue applications; orally bioavailable and brain penetrant
Alternative Names: AkaLumine HCl

Chemical Name: (4S)-2-[(1E,3E)-4-[4-(Dimethylamino)phenyl]-1,3-butadien-1-yl]-4,5-dihydro-4-thiazolecarboxylic acid hydrochloride

Purity: ≥90%

Product Details

Biological Activity

TokeOni is a near-infrared red (NIR)-emission luciferin analog. Peak luminescence at 677 nM. ~40-fold brighter than the luciferin-luciferase system in vitro, and 100-1000 times brighter in vivo. Allows non-invasive visualization of single cells deep inside freely moving animals. Ideal for deep tissue applications. Water soluble (<40 mM), orally bioavailable and brain penetrant.

This product is supplied as a hydrochloride salt, the stoichiometry of which is batch dependant. Please refer to the Certificate of Analysis to obtain the batch specific Net Product Content.

Optical Data for TokeOni

TokeOni Dye Spectra
Emission Color Near-IR
λem 677 nm
Application BLI, BTI, Deep tissue applications

Technical Data

M. Wt
302.39 (Free Base)
Soluble to 5 mg/ml in water with gentle warming and to 10 mg/ml in DMSO
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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