Tolterodine L-tartrate

Catalog # Availability Size / Price Qty
3761/10
3761/50
Non-selective mAChR Antagonists Small Molecule
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Description: Potent, non-selective muscarinic receptor antagonist

Chemical Name: 2-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-methylphenol (2R,3R)-2,3-dihydroxybutanedioate

Purity: ≥99%

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Biological Activity

High affinity muscarinic receptor antagonist (Ki = 3.3 nM). Active at all muscarinic receptor subtypes (M1 - M5); exhibits a greater effect on the bladder than salivary glands in vivo.

Technical Data

M.Wt:
475.57
Formula:
C22H31NO.C4H6O6
Solubility:
Soluble to 10 mM in water and to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
124937-52-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.

Background References

  1. Tolterodine - a new bladder-selective antimuscarinic agent.
    Nilvebrant et al.
    Eur.J.Pharmacol., 1997;327:195
  2. Clinical experiences with tolter.
    Nilvebrant
    Life Sci., 2001;68:2549

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