Chemical Name: (1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid
Biological Activity A selective, competitive GABAA-ρ antagonist with only minimal effects on GABAA and GABAB receptors (Kb values are 2.1 μM (antagonist), 320 μM (antagonist) and EC50 ~ 500 μM (weak agonist) respectively). Displays 8-fold selectivity for human recombinant ρ1 receptors over ρ2 receptors.
Soluble to 100 mM in water
Store at RT
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