TR 14035

Catalog # Availability Size / Price Qty
6908/50
6908/10
TR 14035 | CAS No. 232271-19-1 | Integrin Receptor Inhibitors
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Description: Potent integrin α4β7 and α4β1 (VLA-4) antagonist; orally bioavailable

Chemical Name: (αS)-α-[(2,6-Dichlorobenzoyl)amino]-2',6'-dimethoxy[1,1'-biphenyl]-4-propanoic acid

Purity: ≥98%

Product Details
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Biological Activity

Potent integrin α4β7 and α4β1 antagonist (IC50 values are 7 and 87 nM, respectively). Inhibits binding of HEK 293 cells to osteopontin forms. Orally bioavailable.

Technical Data

M.Wt:
474.33
Formula:
C24H21Cl2NO5
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
232271-19-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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