Chemical Name: 4-(Butylamino)-1-ethyl-6-methyl 1H-pyrazolo[3,4b]pyridine-5-ethylcarboxylate hydrochloride
Biological ActivityTracazolate hydrochloride is a GABAA receptor modulator. Can potentiate or inhibit recombinant GABAA function depending on subunit combination. Enhances native GABAA receptor function and is anxiolytic following systemic administration in vivo.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Enhancement of benzodiazepine and GABA binding by the novel anxiolytic, tracazolate.
Meiners and Salama
Pharmacological properties of tracazolate: a new non-benzodiazepine anxiolytic agent.
Patel and Malick
Tracazolate reveals a novel type of allosteric interaction with recombinant γ-aminobutyric acidA receptors.
Thompson et al.
Citation for Tracazolate hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Tracazolate hydrochloride include:
1 Citation: Showing 1 - 1
Synaptic GABAA receptor clustering without the γ2 subunit.
Authors: Kerti-Szigeti Et al.
J Neurosci 2014;34:10219
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