TRAM/TICAM2 Antibody

Novus Biologicals | Catalog # NBP2-24686

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Bovine, Opossum, Primate

Predicted:

Canine (100%), Chicken (100%), Equine (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all TRAM/TICAM2 Primary Antibodies »

Product Specifications

Immunogen

A portion of amino acids 150-200 of TAG/TIRAP3b was used as the immunogen.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TRAM/TICAM2 Antibody

Western Blot: TRAM/TICAM2 Antibody [NBP2-24686]

Western Blot: TRAM/TICAM2 Antibody [NBP2-24686]

Western Blot: TRAM/TICAM2 Antibody [NBP2-24686] - Analysis of TICAM2 in K562 cell lysate in the 1) absence and 2) presence of immunizing peptide using NBP2-24686 at 3 ug/ml.
Immunohistochemistry-Paraffin: TRAM/TICAM2 Antibody [NBP2-24686]

Immunohistochemistry-Paraffin: TRAM/TICAM2 Antibody [NBP2-24686]

Immunohistochemistry-Paraffin: TRAM/TICAM2 Antibody [NBP2-24686] - Analysis of TAG/TIRAP3b in formalin-fixed, paraffin-embedded human brain tissue using an isotype control (top left) and this antibody (bottom left, right) at 5 ug/ml.

Applications for TRAM/TICAM2 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

2-4 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRAM/TICAM2

TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1-3). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-kappaB (5). Expression of TIRP appears to be essential for TLR4 signalling (6).

Long Name

TRIF-related Adapter Molecule

Alternate Names

TICAM2, TIRAP3, TIRP, Trif

Gene Symbol

TICAM2

Additional TRAM/TICAM2 Products

Product Documents for TRAM/TICAM2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for TRAM/TICAM2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customer Reviews for TRAM/TICAM2 Antibody

There are currently no reviews for this product. Be the first to review TRAM/TICAM2 Antibody and earn rewards!

Have you used TRAM/TICAM2 Antibody?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies