- Products
- products background image
- Services
- Protein Custom Services
- Assay Custom Services
- Antibody Custom Services
- Monoclonal Antibody Panels
- Recombinant Antibody Conversion
- Luminex Custom Services
- Custom Cell Culture Media Services
- Biomarker Testing Services
- Chemistry Services
- Custom Compound Libraries
- Bioactivity Testing Services
- Bulk/Custom Formulation
- Ubiquitin/Proteasome Custom Services
- Custom cDNA Cloning
Expedite Your Research
Expedite Your Research
- Pathways
- Resources
- Research Areas
- Protocols/Troubleshooting Guides/Videos
- Technical Information
- Articles
- Help & FAQs
- Literature
- Request Literature
- Calculators
- Posters
- Blog
- Promotions
- Travel Grants
Posters, Brochures, Whitepapers & Reference Guides
Request Literature
- R&D Systems Quality
- Quality Philosophy
- People
- Place
- Performance
- Product Development
- Customer Satisfaction
- The R&D Systems Quality Advantage
- Documents, Certifications, & FAQs
Experts in Reagent Quality
quality background
- About Us
- Careers
- Bio-Techne Brands
- Investor Relations
Our People are Our Greatest Asset
Join Us
- Contact Us
Catalog Number:3619
Alternate Names:Homotaurine
Chemical Name:3-Amino-1-propanesulfonic acid
Product Details
Reviews
Biological Activity
Sulfated glycosaminoglycan (sGAG) mimetic that targets soluble amyloid β (Aβ) and maintains Aβ in a non-fibrillar form. Decreases Aβ42-induced neuronal death and inhibits amyloid deposition in vitro. Decreases brain amyloid plaque load by 30%, increases tau polymerization and is brain penetrant. Also a GABA analog that protects against the convulsant and cytotoxic activity of kainic acid in vivo.
Sulfated glycosaminoglycan (sGAG) mimetic that targets soluble amyloid β (Aβ) and maintains Aβ in a non-fibrillar form. Decreases Aβ42-induced neuronal death and inhibits amyloid deposition in vitro. Decreases brain amyloid plaque load by 30%, increases tau polymerization and is brain penetrant. Also a GABA analog that protects against the convulsant and cytotoxic activity of kainic acid in vivo.
Technical Data
-
M.Wt:139.17
-
Formula:C3H9NO3S
-
Solubility:Soluble to 100 mM in water
-
Storage:Store at +4°C
-
CAS No:3687-18-1
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Product Datasheets
Tocris Bioscience is the leading supplier of novel and exclusive tools for
life science research with over 30 years' experience in the industry.
Tocris is a Bio-Techne brand.