10 results for "Amyloid beta Peptides" in Products

Amyloid beta Peptides

Amyloid β (Aβ) peptides are the major component of amyloid plaques found in the brains of Alzheimer's patients. Aβ is formed from the progressive cleavage of amyloid precursor protein (APP) by β- and γ-secretase. Two Aβ peptides are formed from APP degradation; Aβ40 and Aβ42. Aβ40 is the most abundant form, but Aβ42 is more fibrillogenic, thus is associated with disease states.

Mutations in APP have been linked to early onset Alzheimer's ...

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Brain penetrant fluorescent amyloid β probe. Used for: detection and quantification of plaques, tangles and cerebrovascular amyloid. Application: confocal microscopy, suitable for in vivo imaging

Chemical Name: 4,4'-[(2-methoxy-1,4-phenylene)di-(1E)-2,1-ethenediyl]bisphenol
Purity: ≥98%
Fluorescent amyloid β detector; brain penetrant
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Predominant amyloid β-protein fragment

Purity: ≥95%
Predominant amyloid β-protein fragment
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Amyloid β-protein fragment

Purity: ≥95%
Amyloid β-protein fragment
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Antiallergic; inhibits inflammatory mediator release from mast cells

Chemical Name: 2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl]amino]benzoic acid
Purity: ≥98%
Antiallergic; inhibits inflammatory mediator release from mast cells
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STAT3 activator; also protects against β-amyloid neurotoxicity

Purity: ≥95%
STAT3 activator; also protects against β-amyloid neurotoxicity
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Cell-permeable fluorescent amyloid stain. Used for: in vitro Aβ staining in brain tissues.

Chemical Name: 2-[4-(Dimethylamino)phenyl]-3,6-dimethylbenzothiazolium chloride
Purity: ≥95%
Fluorescent amyloid stain, binds to the stacked β sheets of amyloid fibrils
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Amyloid fibril-specific fluorescent probe. Used for: amyloid fibril detection. Application: fluorescence microscopy, confocal microscopy

Chemical Name: 4,4'-[(2-Bromo-1,4-phenylene)di-(1E)-2,1-ethenediyl]bisphenol
Purity: ≥98%
Amyloid fibril-specific fluorescent dye
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Potent and selective ERβ agonist; neuroprotective

Chemical Name: 4-[4,4-Difluoro-1-(2-fluorophenyl)cyclohexyl]phenol
Purity: ≥98%
Potent and selective ERβ agonist; neuroprotective
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Neuroprotective and neurotrophic compound; reduces Aβ40 and Aβ42 levels

Chemical Name: 2,2,2-Trifluoroacetic acid 1-(2,4-Dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide
Purity: ≥98%
Neuroprotective and neurotrophic compound; reduces Aβ40 and Aβ42 levels
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BACE1 and BACE2 inhibitor

Chemical Name: N-[3-[(5R)-3-Amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide
Purity: ≥98%
BACE1 and BACE2 inhibitor
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