trans-4-Hydroxycrotonic acid

Key Product Details

Product Description

Binds to the γ-hydroxybutyric acid (GHB) receptor with higher affinity than GHB itself. May be an endogenous ligand.

Product Specifications for trans-4-Hydroxycrotonic acid

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for trans-4-Hydroxycrotonic acid

The following data is based on the product molecular weight 102.09.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	9.80 mL	48.98 mL	97.95 mL
5 mM	1.96 mL	9.80 mL	19.59 mL
10 mM	0.98 mL	4.90 mL	9.80 mL
50 mM	0.20 mL	0.98 mL	1.96 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Hechler Gamma hydroxybutyrate ligands posses antiDArgic and neuroleptic-like activities. J.Pharmacol.Exp.Ther. 1993 PMID: 8095552
• Vayer Natural occurrence of trans-gamma hydroxycrotonic acid in rat brain. Biochem.Pharmacol. 1985 PMID: 4015683
• Bourguignon Analogues of γ-hydroxybutyric acid. Synthesis and binding studies. J.Med.Chem. 1988 PMID: 3361576

Product Documents for trans-4-Hydroxycrotonic acid