Catalog Number: 0538
Chemical Name: trans-4-Hydroxy-2-butenoic acid
Biological Activity
Binds to the γ-hydroxybutyric acid (GHB) receptor with higher affinity than GHB itself.� May be an endogenous ligand.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Analogues of γ-hydroxybutyric acid. Synthesis and binding studies.
    Bourguignon et al.
    J.Med.Chem., 1988;31:893
  2. Gamma hydroxybutyrate ligands posses antidopaminergic and neuroleptic-like activities.
    Hechler et al.
    J.Pharmacol.Exp.Ther., 1993;264:1406
  3. Natural occurrence of trans-gamma hydroxycrotonic acid in rat brain.
    Vayer et al.
    Biochem.Pharmacol., 1985;34:2401
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details


Contact Information

Molarity Calculator
Calculate the mass, volume or concentration required for a solution

The molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) x Volume (L) x Molecular Weight (g/mol)
An example of a molarity calculation using the molarity calculator:
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?

R&D Systems Guarantee

or select another batch:


Customer Information