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TRC 051384

Catalog #: 4734 Datasheet / COA / SDS

Discontinued Product

4734 has been discontinued.
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TRC 051384 | CAS No. 867164-40-7 | HSP70 Modulators
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Description: Inducer of heat shock protein Hsp70

Chemical Name: N-[2-(4-Morpholinyl)ethyl]-N'-[4-[3-[6-(4-morpholinyl)-2-pyridinyl]-1-oxo-2-propen-1-yl]phenyl]urea

Purity: ≥98%

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Biological Activity

TRC 051384 is a inducer of heat shock protein Hsp70; reduces stroke-associated neuronal injury and increases survival in a rat model of transient ischemic stroke. Activates heat shock factor-1 and results in elevated chaperone and anti-inflammatory activity. Enhances Hsp72 expression in neurons and glial cells.

Technical Data

M.Wt:
465.54
Formula:
C25H31N5O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
867164-40-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Delayed intervention in experimental stroke with TRC051384--a small molecule HSP70 inducer.
    Mohanan et al.
    Neuropharmacology., 2011;60:991

Product Datasheets

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