TRO 19622

Catalog # Availability Size / Price Qty
2906/10
2906/50

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TRO 19622 | CAS No. 22033-87-0 | Ion Channel Modulators
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Description: Binds voltage-dependent anion channel (VDAC)
Alternative Names: Olesoxime

Chemical Name: Cholest-4-en-3-one oxime

Purity: ≥98%

Product Details
Citations (2)
Reviews

Biological Activity

TRO 19622 is a neuroprotective and neuroregenerative compound. Rescues motor neurons from axotomy-induced cell death and promotes nerve regeneration following sciatic nerve crush in vivo. Binds directly to two components of the mitochondrial permeability pore, the voltage-dependent anion channel (VDAC) and translocator protein; thought to inhibit MPTP opening.

Technical Data

M.Wt:
399.65
Formula:
C27H45NO
Solubility:
Soluble to 50 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Desiccate at +4°C
CAS No:
22033-87-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for TRO 19622

The citations listed below are publications that use Tocris products. Selected citations for TRO 19622 include:

2 Citations: Showing 1 - 2

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