Chemical Name: 4-[(4-Fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]-benzenepropanoic acid
Biological ActivityPotent FFA4 (GPR120) agonist (pEC 50 values are 7.36 and 7.77 for human and mouse GPR120 respectively). Selective for GPR120 over free fatty acid receptors (pEC 50 = 4.19 for FFA1; displays no activity at FFA2 or FFA3). Cell permeable.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Discovery of a potent and selective GPR120 agonist.
Shimpukade et al.
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VersaClone cDNA Plasmids
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