Home / Free Fatty Acid Receptor Agonists / TUG 891

TUG 891

Catalog #: 4601
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4601/50
TUG 891 | CAS No. 1374516-07-0 | Free Fatty Acid Receptor Agonists
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Description: Potent and selective FFA4 (GPR120) agonist

Chemical Name: 4-[(4-Fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]-benzenepropanoic acid

Purity: ≥99%

Product Details
Citations (1)
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Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

TUG 891 is a potent FFA4 (GPR120) agonist (pEC50 values are 7.36 and 7.77 for human and mouse GPR120 respectively). Selective for GPR120 over free fatty acid receptors (pEC50 = 4.19 for FFA1; displays no activity at FFA2 or FFA3). Cell permeable.

Technical Data

M.Wt:
364.41
Formula:
C23H21FO3
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
1374516-07-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from the University of Southern Denmark.

Background References

  1. Discovery of a potent and selective GPR120 agonist.
    Shimpukade et al.
    J.Med.Chem., 2012;55:4511

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Citation for TUG 891

The citations listed below are publications that use Tocris products. Selected citations for TUG 891 include:

1 Citation: Showing 1 - 1

  1. Docosahexaenoic acid (DHA) effects on proliferation and steroidogenesis of bovine granulosa cells.
    Authors: Maillard Et al.
    Reprod Biol Endocrinol  2018;16:40

FAQs

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VersaClone cDNA Plasmids

Human FFAR4/GPR120 (NP_001182684) VersaClone cDNA

RDC0511

Human FFAR4/GPR120 (NP_859529) VersaClone cDNA

RDC0637

Mouse FFAR4/GPR120/O3FAR1 (NP_861413) VersaClone cDNA

RDC0803

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