UAMC 00039 dihydrochloride

Key Product Details

Product Description

UAMC 00039 dihydrochloride is a potent inhibitor of dipeptidyl peptidase II (DPP-II) (IC₅₀ = 0.48 nM). Exhibits selectivity for DPP-II against DPP-9, DPP-8 and DPP-IV (IC₅₀ values are 78.6, 142 and 165 μM, respectively). Orally available.

Product Specifications for UAMC 00039 dihydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for UAMC 00039 dihydrochloride

The following data is based on the product molecular weight 382.76.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.61 mL	13.06 mL	26.13 mL
5 mM	0.52 mL	2.61 mL	5.23 mL
10 mM	0.26 mL	1.31 mL	2.61 mL
50 mM	0.05 mL	0.26 mL	0.52 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

• Maes Dipeptidyl peptidase 8/9-like activity in human leukocytes. J.Leukoc.Biol. 2007 PMID: 17287297
• Van Goethem Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): is DPP8-selectivity an attainable goal? J.Med.Chem. 2011 PMID: 21711053

Product Documents for UAMC 00039 dihydrochloride