UK 5099

Catalog # Availability Size / Price Qty
4186/10
4186/50
Monocarboxylate Transporter Inhibitors Small Molecule
1 Image
Description: MCT inhibitor; also inhibits of pyruvate transport

Chemical Name: 2-Cyano-3-(1-phenyl-1H-indol-3-yl)-2-propenoic acid

Purity: ≥99%

Product Details
Citations (2)
Reviews

Biological Activity

Inhibitor of plasma membrane monocarboxylate transporters (MCTs) and the mitochondrial pyruvate carrier (MPC).

Technical Data

M.Wt:
288.3
Formula:
C18H12N2O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
56396-35-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for UK 5099

The citations listed below are publications that use Tocris products. Selected citations for UK 5099 include:

2 Citations: Showing 1 - 2

  1. The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity.
    Authors: Rauckhorst Et al.
    Mol Metab  2017;6:1468
  2. SCFA transport in rat duodenum.
    Authors: Kaji Et al.
    Nat Chem Biol  2015;308:G188

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for UK 5099

There are currently no reviews for this product. Be the first to review UK 5099 and earn rewards!

Have you used UK 5099?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.