Chemical Name: 4-[(Diphenylmethoxy)methyl]-1-[3-(4-methoxyphenyl)propyl]-piperidine hydrochloride
Biological Activity Blocker of the KV1.3 and KV1.4 voltage-gated potassium channels in T lymphocytes (IC50 values are 0.28 and 0.17 μM respectively). Suppresses T lymphocyte mitogenesis; leads to membrane depolarization. Also blocks KV1.4 expressed in heart and brain.
Soluble to 50 mM in DMSO and to 30 mM in ethanol
Store at -20°C
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