UK 78282 hydrochloride

Catalog # Availability Size / Price Qty
3829/10
3829/50
UK 78282 hydrochloride | CAS No. 136647-02-4 | Voltage-gated Potassium Channel Blockers
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Description: Blocker of KV1.3 and KV1.4 channels

Chemical Name: 4-[(Diphenylmethoxy)methyl]-1-[3-(4-methoxyphenyl)propyl]-piperidine hydrochloride

Purity: ≥99%

Product Details
Reviews (1)

Biological Activity

Blocker of the KV1.3 and KV1.4 voltage-gated potassium channels in T lymphocytes (IC50 values are 0.28 and 0.17 μM respectively). Suppresses T lymphocyte mitogenesis; leads to membrane depolarization. Also blocks KV1.4 expressed in heart and brain.

Technical Data

M.Wt:
466.05
Formula:
C29H35NO2.HCl
Solubility:
Soluble to 50 mM in DMSO and to 30 mM in ethanol
Purity:
≥99%
Storage:
Store at -20°C
CAS No:
136647-02-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Voltage gated Kv channel blocker with amazing research potential
By Anonymous on 10/15/2018
Species: Human

Voltage gated Kv channel blocking can be assessed under lab conditions with this product. UK 78782 is an excellent compound to get an understanding of channel blocking of different kind of Kv channel. Was dissolved in ethanol and easy to carry out HPLC on.


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