Recombinant Human ULBP-2 His Protein

Name: Recombinant Human ULBP-2 His Protein
Brand: Novus Biologicals
SKU: NBP2-59528
Price: 1319 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-59528

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Source

Baculovirus

Tag

His

Applications

SDS-PAGE

View all ULBP-2 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a C-Terminal His-tag and corresponding to the amino acids 26-216 of Human ULBP-2

Source:Baculovirus

Amino Acid Sequence: ADPGRADPHS LCYDITVIPK FRPGPRWCAV QGQVDEKTFL HYDCGNKTVT PVSPLGKKLN VTTAWKAQNP VLREVVDILT EQLRDIQLEN YTPKEPLTLQ ARMSCEQKAE GHSSGSWQFS FDGQIFLLFD SEKRMWTTVH PGARKMKEKW ENDKVVAMSF HYFSMGDCIG WLEDFLMGMD STLEPSAGAP LAMSHHHHHH

Purity

>90%, by SDS-PAGE

Endotoxin Level

< 1.0 EU per 1 microgram of protein (determined by LAL method)

Predicted Molecular Mass

22.7 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human ULBP-2 His Protein

SDS-PAGE: Recombinant Human ULBP-2 His Protein [NBP2-59528]

SDS-Page: Recombinant Human ULBP-2 Protein [NBP2-59528] - 15% SDS-PAGE (3ug)

Formulation, Preparation, and Storage

NBP2-59528

Formulation	PBS (pH 7.4), 10% glycerol
Preservative	No Preservative
Concentration	0.5 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ULBP-2

Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signalingpathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands toNKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transductionpathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked theinteraction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system.UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface

Long Name

UL16 Binding Protein-2

Alternate Names

ALCAN-alpha, N2DL2, NKG2DL2, RAET1H, ULBP2

Gene Symbol

ULBP2

Additional ULBP-2 Products

Product Documents for Recombinant Human ULBP-2 His Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Human ULBP-2 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Related Research Areas

Natural Killer T (NKT) Cells

NKG2D Receptors and Ligands

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