UNC 2881

Catalog # Availability Size / Price Qty
6537/5
6537/25
Cat.No. 6537 - UNC 2881 | C25H33N7O2 | CAS No. 1493764-08-1
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Description: Potent Mer kinase inhibitor

Chemical Name: 2-(Butylamino)-4-[(trans-4-hydroxycyclohexyl)amino]-N-[[4-(1H-imidazol-1-yl)phenyl]methyl]-5-pyrimidinecarboxamide

Purity: ≥98%

Product Details
Reviews

Biological Activity

Potent Mer kinase inhibitor. Displays >55-fold selectivity for Mer kinase over other TAM receptor tyrosine kinase family members (IC50 values are 4.3 nM, 0.25 μM and 0.36 μM for Mer, Tyro3 and Alk, respectively). Inhibits Mer phosphorylation in vitro. Also inhibits platelet aggregation in response to Type I collagen.

Technical Data

M.Wt:
463.58
Formula:
C25H33N7O2
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1493764-08-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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