uPAR Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-29589

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all uPAR Primary Antibodies »

Product Specifications

Immunogen

Between 175 and 225

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit uPAR Antibody - BSA Free (NBP3-29589) is a polyclonal antibody validated for use in WB and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for uPAR Antibody - BSA Free

uPAR Antibody

Immunoprecipitation:[NBP3-29589]-

Immunoprecipitation:[NBP3-29589]-Detection of human glycosylated and deglycosylated UPAR by western blot of immunoprecipitates. Samples: Whole cell lysate from U-937 cells incubated with or without TPA and lysed using NETN lysis buffer. The lysate was then treated or mock treated with PnGase F. Antibodies: Affinity purified rabbit anti-UPAR antibody used for IP at 6 µg per reaction. For blotting immunoprecipitated UPAR, was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Applications for uPAR Antibody - BSA Free

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate buffer, pH 7 to 8

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: uPAR

uPAR (Urokinase plasminogen activator receptor) is a glycoprotein I anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum beta globulin plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin-like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis.

Long Name

Urokinase-type Plasminogen Activator Receptor

Alternate Names

PLAUR

Gene Symbol

PLAUR

Additional uPAR Products

Product Documents for uPAR Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for uPAR Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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