UPF 648

Catalog # Availability Size / Price Qty
4926/10
Cat.No. 4926 - UPF 648 | C11H8Cl2O3 | CAS No. 213400-34-1
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Description: Potent kynurenine 3-monooxygenase (KMO) inhibitor

Chemical Name: (1S,2S)-2-(3,4-Dichlorobenzoyl)cyclopropanecarboxylic acid

Purity: ≥98%

Product Details
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Biological Activity

Potent kynurenine 3-monooxygenase (kynurenine 3-hydroxylase; KMO) inhibitor (IC50 = 20 nM). Increases kynurenic acid levels, and decreases 3-HK and QUIN levels in cerebrum and liver of neonatal rodents. Neuroprotective in a Drosophila model of Huntington's disease.

Technical Data

M.Wt:
259.09
Formula:
C11H8Cl2O3
Solubility:
Soluble to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
213400-34-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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