Catalog Number: 1605
Biological Activity
Endogenous CRF agonist. Ki values are 13, 1.5 and 0.97 nM for hCRF1, rCRF2α and mCRF2β respectively.
Technical Data
  • M.Wt:
    4707.31
  • Formula:
    C206H338N62O64
  • Sequence:
    DDPPLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSV

    (Modifications: Val-40 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    171543-83-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold with the permission of the SALK Institute
Background References
  1. The neurobiology of urocortin.
    Skelton et al.
    Regul.Pept., 2000;93:85
  2. Corticotropin-releasing factor receptors 1 and 2 in anxiety and depression.
    Reul and Holsboer
    Curr.Opin.Pharmacol., 2002;2:23
  3. Corticotropin releasing factor receptors and their ligand family.
    Perrin and Vale
    Ann.N.Y.Acad.Sci., 1999;885:312

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