VH 101 phenol-alkylC4-amine

Tocris Bioscience | Catalog # 7293

VHL ligand with alkyl linker and terminal amine for onward chemistry
Tocris Bioscience

Key Product Details

Description

VHL ligand with alkyl linker and terminal amine for onward chemistry
View all Degrader Building Blocks »

Product Description

VH 101 phenol-alkylC4-amine is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC4 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Licensing Information

Sold under licence from the University of Dundee.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Product Specifications for VH 101 phenol-alkylC4-amine

Molecular Weight

676.67

Formula

C30H42FN5O5S.2HCl

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

(2S,4R)-N-(2-(4-Aminobutoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride

CAS Number

2564467-03-2

InChI Key

UQHSXRZQPDIVIY-OTCWRJAQSA-N

SMILES

CC1=C(SC=N1)C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@@H](NC(C4(CC4)F)=O)C(C)(C)C)=O)=O)C(OCCCCN)=C2.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Calculators

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

x
=
x

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product.

There are currently no references for this product.

Product Documents for VH 101 phenol-alkylC4-amine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for VH 101 phenol-alkylC4-amine

For research use only

Customer Reviews for VH 101 phenol-alkylC4-amine

There are currently no reviews for this product. Be the first to review VH 101 phenol-alkylC4-amine and earn rewards!

Have you used VH 101 phenol-alkylC4-amine?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card