Chemical Name: 4-Aminohexenoic acid
Biological ActivityVigabatrin is a selective GABA-T (transaminase) inhibitor. Anticonvulsant.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
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Differential effect of gamma-vinyl GABA and valproate on GABA transaminase from cultured neurones and astrocytes.
Larsson et al.
Vigabatrin modulates benzodiazepine receptor activity in vivo: a positron emission tomography study in baboon.
Schmid et al.
Effects of vigab. (γ-vinyl GABA) on neurotransmission-related amino acids and on GABA and benzodiazepine receptor binding in rats.
Halonen et al.
Citations for Vigabatrin
The citations listed below are publications that use Tocris products. Selected citations for Vigabatrin include:
2 Citations: Showing 1 - 2
Preclinical tissue distribution and metabolic correlations of vigabatrin, an antiepileptic drug associated with potential use-limiting visual field defects.
Authors: Walters Et al.
Pharmacol Res Perspect 2019;7:e00456
Glutamate uptake triggers transporter-mediated GABA release from astrocytes.
Authors: Héja Et al.
Stem Cells Dev 2009;4:e7153
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