Catalog Number: 0808
Alternate Names: (±)-γ-Vinyl GABA
Chemical Name: 4-Aminohexenoic acid
Biological Activity
Selective GABA-T (transaminase) inhibitor. Anticonvulsant.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Differential effect of gamma-vinyl GABA and valproate on GABA transaminase from cultured neurones and astrocytes.
    Larsson et al.
    Neuropharmacology, 1986;25:617
  2. Effects of vigabatrin (γ-vinyl GABA) on neurotransmission-related amino acids and on GABA and benzodiazepine receptor binding in rats.
    Halonen et al.
    Epilepsia, 1991;32:242
  3. Vigabatrin modulates benzodiazepine receptor activity in vivo: a positron emission tomography study in baboon.
    Schmid et al.
    J.Pharmacol.Exp.Ther., 1996;276:977

The citations listed below are publications that use Tocris products. Selected citations for Vigabatrin include:

1 Citations: Showing 1 - 1

  1. Glutamate uptake triggers transporter-mediated GABA release from astrocytes.
    Authors: Héja Et al.
    Stem Cells Dev 2009;4:e7153

Have you used Vigabatrin?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details


Contact Information


Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

or select another batch: 


Customer Information