Chemical Name: 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide
Biological ActivityVismodegib is a potent hedgehog pathway inhibitor (IC50 = 3 nM). It causes tumor regressions in allograft medulloblastoma mice model and tumor growth inhibition in a xenograft mouse models of colorectal cancer. Vismodegib is orally bioavailable.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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