VU 0155041 sodium salt

Key Product Details

Product Description

VU 0155041 sodium salt is a potent, positive allosteric modulator/allosteric agonist at mGlu₄ receptors (EC₅₀ = 798 and 693 nM at human and rat mGlu₄ receptors respectively). Active in in vivo models of Parkinson's disease following i.c.v. administration. Sodium salt of VU 0155041 (Cat. No. 3248).

Product Specifications for VU 0155041 sodium salt

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for VU 0155041 sodium salt

The following data is based on the product molecular weight 338.16.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

4 3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.25 mM	11.83 mL	59.14 mL	118.29 mL
1.25 mM	2.37 mL	11.83 mL	23.66 mL
2.5 mM	1.18 mL	5.91 mL	11.83 mL
12.5 mM	0.24 mL	1.18 mL	2.37 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Niswender Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4. Mol.Pharmacol. 2008 PMID: 18664603

Product Documents for VU 0155041 sodium salt