VU 0361737

Catalog # Availability Size / Price Qty
3707/10
3707/50
VU 0361737 | CAS No. 1161205-04-4 | Group III mGluR Modulators
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Description: Selective positive allosteric modulator of mGlu4 receptors

Chemical Name: N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide

Purity: ≥99%

Product Details
Citations (1)
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Biological Activity

Selective positive allosteric modulator at mGlu4 receptors (EC50 values are 240 and 110 nM at human and rat receptors respectively). Inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors and displays weak activity at mGlu5 and mGlu8 receptors. Brain penetrant.

Technical Data

M.Wt:
262.69
Formula:
C13H11ClN2O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
1161205-04-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for VU 0361737

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