VU 152100

   
Product Datasheet
Catalog Number:3383
Alternate Names:ML 108
Chemical Name:3-Amino-N-(4-methoxybenzyl)-4,6-dimethylthieno[2,3-b]pyridine carboxamide
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Biological Activity
Selective positive allosteric modulator of M4 muscarinic acetylcholine receptors (mAChRs) (EC50 = 380 nM). Induces 21-fold shift in ACh potency at M4 receptor. Displays no activity at other mAChR subtypes.
Technical Data
  • M.Wt:
    341.43
  • Formula:
    C18H19N3O2S
  • Solubility:
    Soluble to 50 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    409351-28-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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