VU 152100

Catalog # Availability Size / Price Qty
3383/10
3383/50
VU 152100 | CAS No. 409351-28-6 | mAChR M4 Modulators
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Description: Positive allosteric modulator of M4 receptors
Alternative Names: ML 108

Chemical Name: 3-Amino-N-(4-methoxybenzyl)-4,6-dimethylthieno[2,3-b]pyridine carboxamide

Purity: ≥98%

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Biological Activity

Selective positive allosteric modulator of M4 muscarinic acetylcholine receptors (mAChRs) (EC50 = 380 nM). Induces 21-fold shift in ACh potency at M4 receptor. Displays no activity at other mAChR subtypes.

Technical Data

M.Wt:
341.43
Formula:
C18H19N3O2S
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
409351-28-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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