VUF 11207 fumarate
Chemical Name: N-[(2E)-3-(2-Fluorophenyl)-2-methyl-2-propen-1-yl]-3,4,5-trimethoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]benzamide fumarate
Purity: ≥98%
Biological Activity
VUF 11207 fumarate is a potent ACKR3 (CXCR7) chemokine receptor agonist (EC50 = 1.6 nM). Induces recruitment of β-arrestin to CXCR7 in HEK293-CXCR7 cells.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Synthesis, modeling and functional activity of substituted styrene-amides as small-molecule CXCR7 agonists.
Wijtmans et al.
Eur.J.Med.Chem., 2012;51:184
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