VUF 11207 fumarate

Tocris Bioscience | Catalog # 4780

Potent ACKR3 (CXCR7) agonist
Tocris Bioscience
Discontinued Product
4780 has been discontinued. View all Chemokine Receptor Agonists products.

Key Product Details

Description

Potent ACKR3 (CXCR7) agonist

Product Description

VUF 11207 fumarate is a potent ACKR3 (CXCR7) chemokine receptor agonist (EC50 = 1.6 nM). Induces recruitment of β-arrestin to CXCR7 in HEK293-CXCR7 cells.

Product Specifications for VUF 11207 fumarate

Molecular Weight

586.65

Formula

C27H35FN2O4.C4H4O4

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

N-[(2E)-3-(2-Fluorophenyl)-2-methyl-2-propen-1-yl]-3,4,5-trimethoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]benzamide fumarate

CAS Number

1785665-61-3

PubChem ID

90488970

InChI Key

MTPOECCHJLVVGO-FDULSSLPSA-N

SMILES

C\C(CN(CCC2N(C)CCC2)C(C3=CC(OC)=C(OC)C(OC)=C3)=O)=C/C1=C(F)C=CC=C1.OC(/C=C/C(O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 58.66 100
DMSO 58.66 100

Preparing Stock Solutions for VUF 11207 fumarate

The following data is based on the product molecular weight 586.65.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.70 mL 8.52 mL 17.05 mL
5 mM 0.34 mL 1.70 mL 3.41 mL
10 mM 0.17 mL 0.85 mL 1.70 mL
50 mM 0.03 mL 0.17 mL 0.34 mL

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Background References

References are publications that support the biological activity of the product.

Product Documents for VUF 11207 fumarate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for VUF 11207 fumarate

For research use only

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