VUF 11222
Description: High affinity non-peptide CXCR3 agonist
Chemical Name: 2'-Bromo-N-[[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]methyl]-N,N-dimethyl-[1,1'-biphenyl]-4-methanaminium iodide
Purity: ≥98%
Biological Activity
High affinity non-peptide CXCR3 agonist (pKi = 7.2).Technical Data
M.Wt:
552.33
Formula:
C25H31BrIN
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol with gentle warming
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1414376-84-3
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Chemical subtleties in small-molecule modulation of peptide receptor function: the case of CXCR3 biaryl-type ligands.
Wijtmans et al.
J.Med.Chem., 2012;55:10572
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