VUF 5574

Key Product Details

Product Description

VUF 5574 is a potent, selective, competitive antagonist for the human adenosine A₃ receptor (K_i = 4 nM). Displays ≥ 2500-fold selectivity over A₁ and A_2A receptors.

Product Specifications for VUF 5574

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for VUF 5574

The following data is based on the product molecular weight 371.39.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.04 mM	67.31 mL	336.57 mL	673.15 mL
0.2 mM	13.46 mL	67.31 mL	134.63 mL
0.4 mM	6.73 mL	33.66 mL	67.31 mL
2 mM	1.35 mL	6.73 mL	13.46 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

• van Muijlwijk-Koezen Isoquinoline and quinazoline urea analogues as antagonists for the human adenosine A₃ receptor. J.Med.Chem. 2000 PMID: 10841801
• Baraldi and Borea New potent and selective human adenosine A₃ receptor antagonists. TiPS 2000 PMID: 11121831

Product Documents for VUF 5574