VUF 5574

  ( 2 citations )    
Product Datasheet
Catalog Number:1359
Chemical Name:N-(2-Methoxyphenyl)-N'-[2-(3-pyrindinyl)-4-quinazolinyl]-urea
Product Details
Citations (2)
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Biological Activity
Potent, selective, competitive antagonist for the human adenosine A3 receptor (Ki = 4 nM). Displays ≥ 2500-fold selectivity over A1 and A2A receptors.
Technical Data
  • M.Wt:
    371.39
  • Formula:
    C21H17N5O2
  • Solubility:
    Soluble to 4 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    280570-45-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for VUF 5574 include:

2 Citations: Showing 1 - 2
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  1. IL-4 amplifies the pro-inflammatory effect of adenosine in human mast cells by changing expression levels of adenosine receptors.
    Authors: Hua Et al.
    PLoS One  2011;6:e24947
  2. A3 adenosine receptor antagonists delay irreversible synaptic failure caused by oxygen and glucose deprivation in the rat CA1 hippocampus in vitro.
    Authors: Pugliese Et al.
    Br J Pharmacol  2006;147:524

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