Calmodulin antagonist. Inhibits Ca
-calmodulin-dependent phosphodiesterase (IC
M) and myosin light chain kinase (IC
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Divergent pharmacological effects of three calmodulin antagonists, N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W 7), chlorpromazine and calmidazolium, on isometric tension development and myosin light chain phosphorylation in intact bovine trachea
Asano et al.
N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation.
Hidaka et al.
Direct interaction of calmodulin antagonists with Ca 2+/calmodulin-dependent cyclic nucleotide phosphodiesterase.
Itoh and Hidaka
Hydrophobic regions function in calmodulin-enzyme(s) interactions.
Tanaka and Hidaka
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