WAY 161503 hydrochloride

  ( 3 citations )    
Product Datasheet
Catalog Number:1801
Chemical Name:8,9-Dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride
Product Details
Citations (3)
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Biological Activity
Potent and selective 5-HT2C receptor agonist (Ki = 4 nM; EC50 = 12 nM). Antidepressant following systemic administration in vivo.
Technical Data
  • M.Wt:
    308.59
  • Formula:
    C11H11Cl2N3O.HCl
  • Purity:
    >99
  • Storage:
    Desiccate at RT
  • CAS No:
    276695-22-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for WAY 161503 hydrochloride include:

3 Citations: Showing 1 - 3
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  1. Monoaminergic modulation of GABAergic transmission onto cerebellar globular cells.
    Authors: Hirono
    Neuropharmacology  2017;118:79
  2. 5-HT2C receptor agonist anorectic efficacy potentiated by 5-HT1B receptor agonist coapplication: an effect mediated via increased proportion of pro-opiomelanocortin neurons activated.
    Authors: Doslikova Et al.
    J Neurosci  2013;33:9800
  3. Deconstructing antiobesity compound action: requirement of serotonin 5-HT2B receptors for dexfenfluramine anorectic effects.
    Authors: Banas Et al.
    Neuropsychopharmacology  2011;36:423

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