WAY 207024 dihydrochloride

Key Product Details

Product Description

WAY 207024 dihydrochloride is a gonadotropin releasing hormone receptor (GnRH-R) antagonist. Exhibits potent affinity (IC₅₀ values are 12 and 71 nM for human and rat GnRH receptors respectively). Lowers plasma leuteinizing hormone levels in the rat. Orally active.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Product Specifications for WAY 207024 dihydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for WAY 207024 dihydrochloride

The following data is based on the product molecular weight 549.54.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.85 mM	2.14 mL	10.70 mL	21.41 mL
4.25 mM	0.43 mL	2.14 mL	4.28 mL
8.5 mM	0.21 mL	1.07 mL	2.14 mL
42.5 mM	0.04 mL	0.21 mL	0.43 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Pelletier Discovery of 6-({4-[2-(4-tert-butylphenyl)-1H-benzimidazol-4-yl]piperazin-1-yl}methyl)quinoxaline (WAY-207024): an orally active antagonist of the g.tropin releasing hormone receptor (GnRH-R). J.Med.Chem. 2009 PMID: 19072222

Product Documents for WAY 207024 dihydrochloride