WAY 208466 dihydrochloride
Chemical Name: 3-[(-3-Fluorophenyl)sulfonyl]-N,N-dimethyl-1H-pyrrolo[2,3-b]pyridine-1-ethanamine dihydrochloride
Biological ActivityHigh affinity, selective 5-HT6 agonist (EC50 = 7.3 nM at the human 5-HT6 receptor). Elevates cortical GABA levels in vivo in rat frontal cortex. Exhibits antidepressant and anxiolytic-like effects.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Neuropharmacological profile of novel and selective 5-HT6 receptor agonists: WAY-181187 and WAY-208466.
Schechter et al.
Antidepressant and anxiolytic effects of selective 5-HT6 receptor agonists in rats.
Carr et al.
Citation for WAY 208466 dihydrochloride
The citations listed below are publications that use Tocris products. Selected citations for WAY 208466 dihydrochloride include:
1 Citation: Showing 1 - 1
Activation and blockade of basolateral amygdala 5-HT6 receptor produce anxiolytic-like behaviors in an experimental model of Parkinson's disease.
Authors: Sun Et al.
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