WAY 208466 dihydrochloride

Tocris Bioscience | Catalog # 3904

Selective 5-HT6 agonist
Tocris Bioscience

Key Product Details

Description

Selective 5-HT6 agonist
View all 5-HT6 Receptor Agonists »

Product Description

WAY 208466 dihydrochloride is a high affinity, selective 5-HT6 agonist (EC50 = 7.3 nM at the human 5-HT6 receptor). Elevates cortical GABA levels in vivo in rat frontal cortex. Exhibits antidepressant and anxiolytic-like effects.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Product Specifications for WAY 208466 dihydrochloride

Molecular Weight

420.33

Formula

C17H18FN3O2S.2HCl

Storage

Desiccate at RT

Purity

≥99% (HPLC)

Chemical Name

3-[(-3-Fluorophenyl)sulfonyl]-N,N-dimethyl-1H-pyrrolo[2,3-b]pyridine-1-ethanamine dihydrochloride

CAS Number

1207064-61-6

PubChem ID

22028182

InChI Key

BAOHMLBVCLITHA-UHFFFAOYSA-N

SMILES

O=S(C2=CN(CCN(C)C)C1=NC=CC=C12)(C3=CC=CC(F)=C3)=O.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 33.63 80
DMSO 33.63 80

Preparing Stock Solutions for WAY 208466 dihydrochloride

The following data is based on the product molecular weight 420.33.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.8 mM 2.97 mL 14.87 mL 29.74 mL
4 mM 0.59 mL 2.97 mL 5.95 mL
8 mM 0.30 mL 1.49 mL 2.97 mL
40 mM 0.06 mL 0.30 mL 0.59 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

Product Documents for WAY 208466 dihydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for WAY 208466 dihydrochloride

For research use only

Citations for WAY 208466 dihydrochloride

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