WAY 316606 hydrochloride
Tocris Bioscience | Catalog # 4767
Key Product Details
Description
Product Description
WAY 316606 hydrochloride is a secreted Frizzled-Related Protein-1 (sFRP-1) inhibitor (IC50 = 0.65 μM); prevents sFRP-1 from interacting with Wnt and thus increases Wnt signaling. Increases total bone area in a murine calvarial organ culture assay.
We are aware of a study in PLOS Biology where WAY-316606 was found to stimulate hair follicle growth. Please note that WAY-316606 from Tocris is for laboratory research use only, and that we will only sell to established scientific businesses and institutes.
Product Specifications for WAY 316606 hydrochloride
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 9.7 | 20 |
Preparing Stock Solutions for WAY 316606 hydrochloride
The following data is based on the product molecular weight 484.94.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.2 mM | 10.31 mL | 51.55 mL | 103.11 mL |
| 1 mM | 2.06 mL | 10.31 mL | 20.62 mL |
| 2 mM | 1.03 mL | 5.16 mL | 10.31 mL |
| 10 mM | 0.21 mL | 1.03 mL | 2.06 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.
- Moore Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides. J.Med.Chem. 2009 PMID: 19072540
- Bodine A small molecule inhibitor of the Wnt antagonist secreted frizzled-related protein-1 stimulates bone formation. Bone 2009 PMID: 19254787
- Moore Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides: part II. Bioorg.Med.Chem. 2010 PMID: 19932972
Product Documents for WAY 316606 hydrochloride
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for WAY 316606 hydrochloride
For research use only
Citations for WAY 316606 hydrochloride
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Species: HumanVerified Customer | Posted 06/28/2020We are a reference lab and needed to compare a questioned product to authentic WAY-316606. We generated our own purity and identity information on this product and confirmed the COA. The attached PDF shows that the infrared spectrum was an exact match with the questioned material. That's exactly what we needed to confirm.
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FAQs for WAY 316606 hydrochloride
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Q: I have seen the recent news reports that indicate this product can be used to cure baldness. I would like to know how I would place an order or use the product to prevent further hair loss or stimulate hair growth.
A: I'm sorry for your loss but we will not be able to help you. This product is intended for research use only by trained scientific professionals. It must not under any circumstances be used for human, drug, food, cosmetic, agricultural, domestic or any other unapproved consumer purpose.
This product has not undergone the rigorous testing, regulatory inspections and approvals that would be required for a pharmaceutical grade product. We cannot legally sell these products for personal use.