WEB 2086

  ( 6 citations )    
Product Datasheet
Catalog Number:2339
Alternate Names:Apafant
Chemical Name:4-[3-[4[(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a]diazepin-2-yl]-1-oxopropyl]morpholine
Product Details
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Biological Activity
Potent, selective platelet-activating factor (PAF) receptor antagonist (Ki = 16.3 nM). Displays anti-inflammatory, antiangiogenic and anticancer activity. Inhibits growth and proliferation of MCF-7 breast cancer cells.
Technical Data
  • M.Wt:
    455.96
  • Formula:
    C22H22N5O2SCl
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol with gentle warming
  • Purity:
    >99
  • Storage:
    Desiccate at +4°C
  • CAS No:
    105219-56-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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