Home / Aldehyde Dehydrogenase Inhibitors / WIN 18446

WIN 18446

Catalog #: 4736
1 Citation Datasheet / COA / SDS
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4736/50
WIN 18446 | CAS No. 1477-57-2 | Aldehyde Dehydrogenase Inhibitors
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Description: ALDH1A2 inhibitor

Chemical Name: N,N'-1,8-Octanediylbis(2,2-dichloroacetamide)

Product Details
Citations (1)
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Biological Activity

WIN 18446 is an inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2) (IC50 = 0.3 μM). Inhibits the biosynthesis of retinoic acid from retinol in neonatal and adult murine testis.

Technical Data

M.Wt:
366.11
Formula:
C12H20Cl4N2O2
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Storage:
Store at +4°C
CAS No:
1477-57-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for WIN 18446

The citations listed below are publications that use Tocris products. Selected citations for WIN 18446 include:

1 Citation: Showing 1 - 1

  1. Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration.
    Authors: Barrionuevo Et al.
    Elife  2016;5

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