WKYMVM

Name: WKYMVM
Brand: Tocris Bioscience
SKU: 1799

Tocris Bioscience | Catalog # 1799

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Citations (15)

Product Documents

Selective FPR2 and FPR3 receptor agonist

Discontinued Product

1799 has been discontinued. View all Formyl Peptide Receptor Agonists products.

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Selective FPR2 and FPR3 receptor agonist

Alternative Names

W-peptide

View all Formyl Peptide Receptor Agonists »

Product Description

WKYMVM is a selective agonist for the formyl peptide receptors FPR2 and FPR3, expressed on immune cells. EC₅₀ values for induction of calcium mobilization in FPR2-HL-60 cells and FPR3-HL-60 cells are 2 and 80 nM respectively.

Product Specifications for WKYMVM

Molecular Weight

856.11

Formula

C₄₁H₆₁N₉O₇S₂

Storage

Desiccate at -20°C

CAS Number

187986-11-4

PubChem ID

68661247

InChI Key

FMBGOORJEKQQLG-LXOXETEGSA-N

SMILES

[H]N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 0.6mg/ml in water

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 15 publications citing the usage of this product.

Christophe The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH₂ specifically activates neutrophils through FPRL1/Lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2. J.Biol.Chem. 2001 PMID: 11285256
Christophe Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1 /LXA4R, is not affected by lipoxin. Scand.J.Immunol. 2002 PMID: 12410796
Baek Identification of the peptides that stimulate the phosphoinositide hydrolysis in lymphocyte cell lines from peptide libraries. J.Biol.Chem. 1996 PMID: 8626507

Product Documents for WKYMVM

Certificate of Analysis

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Product Specific Notices for WKYMVM

For research use only

Citations for WKYMVM

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