WS 3
Chemical Name: N-Ethyl-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide
Purity: ≥99%
Biological Activity
Cooling agent that is an agonist at TRPM8 receptors (EC50 = 3.7 μM).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay.
Behrendt et al.
Br.J.Pharmacol., 2004;141:737 -
TRP proteins and cancer.
Bodding
Cell Signal., 2007;19:617 -
Better than mint.
Rovner
C&EN, 2007;85:95
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