WS 3

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WS 3 | CAS No. 39711-79-0 | TRPM Agonists
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Description: TRPM8 agonist; cooling agent

Chemical Name: N-Ethyl-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide

Purity: ≥99%

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Biological Activity

Cooling agent that is an agonist at TRPM8 receptors (EC50 = 3.7 μM).

Technical Data

M.Wt:
211.34
Formula:
C13H25NO
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
39711-79-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay.
    Behrendt et al.
    Br.J.Pharmacol., 2004;141:737
  2. TRP proteins and cancer.
    Bodding
    Cell Signal., 2007;19:617
  3. Better than mint.
    Rovner
    C&EN, 2007;85:95

Product Datasheets

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