Catalog Number: 2927
Chemical Name: N-Ethyl-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide
Biological Activity
Cooling agent that is an agonist at TRPM8 receptors (EC50 = 3.7 μM).
Technical Data
  • M.Wt:
    211.34
  • Formula:
    C13H25NO
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    39711-79-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay.
    Behrendt et al.
    Br.J.Pharmacol., 2004;141:737
  2. TRP proteins and cancer.
    Bodding
    Cell Signal., 2007;19:617
  3. Better than mint.
    Rovner
    C&EN, 2007;85:95

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