values are 0.63, 32 and > 100 μ
M at PPARα
respectively). Negatively inhibits NF-κ
B transcriptional activity and decreases the inflammatory response in vitro
and in vivo
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
The PPARs: from orphan receptors to drug discovery.
Willson et al.
Peroxisome proliferator-activated receptors in the cardiovascular system.
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ.
Forman et al.
The citations listed below are publications that use Tocris products. Selected citations for WY 14643 include:
Showing Results 1 - 6 of 6