Xanthohumol

Catalog # Availability Size / Price Qty
4686/10
Cat.No. 4686 - Xanthohumol | C21H22O5 | CAS No. 6754-58-1
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Description: p97 ATPase (VCP) inhibitor

Chemical Name: (2E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one

Product Details
Citations (1)
Reviews

Biological Activity

p97 ATPase (VCP) inhibitor. Binds to the N domain of p97, impairing autophagosome function and maturation. Inhibits proliferation and induces apoptosis in a variety of human cancer cell lines. Also inhibits DGAT in rat liver microsomes (IC50 = 50.3 μM).

Technical Data

Formula:
C21H22O5
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage:
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
CAS No:
6754-58-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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Citation for Xanthohumol

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