Chemical Name:[2-[[8-(Dimethylamino)octyl]thio]-6-(1-methylethyl)-3-pyridinyl]-2-thienylmethanone oxalate
Biological Activity Inhibitor of prolyl endopeptidase, a serine peptidase that may be implicated in the biosynthesis of amyloid β-peptide. Potently inhibits rat brain prolyl endopeptidase (Ki = 0.95 nM) in vitro, and prevents amyloid β-peptide deposition in vivo. Orally active and brain penetrant.
Soluble to 15 mM in ethanol with gentle warming and to 15 mM in DMSO
Store at -20°C
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For batch specific data refer to the Certificate of Analysis.
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