Chemical Name: [2-[[8-(Dimethylamino)octyl]thio]-6-(1-methylethyl)-3-pyridinyl]-2-thienylmethanone oxalate
Biological ActivityY-29794 oxalate is a inhibitor of prolyl endopeptidase, a serine peptidase that may be implicated in the biosynthesis of amyloid β-peptide. Potently inhibits rat brain prolyl endopeptidase (Ki = 0.95 nM) in vitro, and prevents amyloid β-peptide deposition in vivo. Orally active and brain penetrant.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Prevention of amyloid-like deposition by a selective prolyl endopeptidase inhibitor, Y-29794, in senescence-accelerated mouse.
Kato et al.
Y-29794 - a non-peptide prolyl endopeptidase inhibitor that can penetrate into the brain.
Nakajima et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for Y-29794 oxalate
There are currently no reviews for this product. Be the first to review Y-29794 oxalate and earn rewards!
Have you used Y-29794 oxalate?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image